Dr Daniel Gale

Rare Disease Medical Lead

Daniel Gale is the St Peter’s Associate Professor of Nephrology at the UCL Department of Renal Medicine, Royal Free Hospital where he leads the North/Central Thames renal genetics service, delivering specialised care for patients and families with hereditary kidney problems including polycystic kidney disease, aHUS, Alport Syndrome and unexplained familial kidney failure.

He described and identified the molecular defects responsible for the genetic diseases HIF2α erythrocytosis with pulmonary hypertension, which results from a defect in cellular oxygen sensing, and CFHR5 nephropathy, which results from a defect of complement regulation and is endemic in people of Cypriot ancestry.

He also oversees the RaDaR rare renal disease registry of 25,000 patients with rare kidney diseases from across the UK.